International scientific journal "Modern Science and Research"

ISSN: 2181-3906;   OAV Guvohnoma №042359;   Impact factor (UIF-2022): 8.2
Ushbu jurnalda O'zbekiston va chet davlatlar olimlari ilmiy maqolalari chop etiladi.
Ushbu jurnal OAK ro'yxatida mavjud xalqaro bazalarda indekslanib, elektron va bosma holatda nashr etib boriladi.
Jurnalning rasmiy tillari: o‘zbek, rus, ingliz
Jurnal telegram kanali: https://t.me/modernscience_research
Maqola muallifiga BEPUL qabul qilinganlik haqida tabriknoma, sertifikat, indekslanganligi haqida ma'lumotnoma va mualliflik guvohnomasi beriladi.
Jurnal har oyda nashr qilinadi.
Maqolalar yuborish uchun: @modernscience_research
golibboymurodov6@gmail.com

Articles Information letter

Oxirgi qushilgan maqolalar:



XVIII – XIX ASR OXIRIGACHA DAVRDA SHIMOLIY SURXON VOHASIDAGI BEKLIKLARNING MA’MURIY-HUDUDIY BO’LINISHI

Surxon vohasida esa Sherobod, Denov, Boysun, Sarijo’y va Yurchi kabi bekliklar bo’lgan va bular turli davrlarda tashkil etilib yugatilib turilgan. Ushbu maqolada esa Surxon vohasining shimoliy qismida joylashgan bekliklarni tadqiq qilamiz.


20.05.2025 Volume 4 Issue 5 View more Download
SPORT TADBIRLARIDA MARKETING STRATEGIYALARINING AHAMIYATI VA ULARNING SAMARADORLIGI

Mazkur maqolada sport tadbirlarida marketing strategiyalarining tutgan o‘rni, ularning qo‘llanilish shakllari va samaradorlik darajasi har tomonlama tahlil qilinadi. Sport sohasi zamonaviy jamiyatda nafaqat sog‘lom turmush tarzini targ‘ib qiluvchi ijtimoiy institut, balki katta iqtisodiy salohiyatga ega bo‘lgan tarmoq sifatida ham maydonga chiqmoqda. Xususan, yirik sport tadbirlarining muvaffaqiyatli tashkil etilishi ularning marketing jihatdan to‘g‘ri rejalashtirilganligiga bog‘liq. Maqolada sport marketingining asosiy strategiyalari — brending, raqamli marketing, homiylik aloqalari, auditoriya bilan ishlash va tomoshabinlar tajribasini boshqarish kabi yo‘nalishlar alohida ko‘rib chiqiladi.


20.05.2025 Volume 4 Issue 5 View more Download
PATHOPHYSIOLOGICAL BASIS AND HORMONAL FACTORS OF THE DEVELOPMENT OF HYPERTENSION

This article explores the pathophysiological mechanisms underlying the development of hypertension, with a special emphasis on the hormonal factors that contribute to elevated blood pressure. Hypertension, one of the most prevalent cardiovascular disorders worldwide, results from a complex interplay between genetic predisposition, environmental influences, and dysregulation of multiple physiological systems. The article discusses how alterations in renal function, vascular resistance, and sympathetic nervous system activity lead to chronic elevation of arterial pressure. Particular attention is given to the renin-angiotensin-aldosterone system (RAAS), vasopressin, and other endocrine factors such as catecholamines and natriuretic peptides. The review also highlights the feedback loops and receptor sensitivities that sustain hypertensive states over time. Understanding these hormonal contributions is essential for identifying therapeutic targets and improving the management of hypertensive patients. Overall, the paper aims to provide a comprehensive view of how hormonal imbalance acts as a key driver in the pathogenesis of hypertension.


20.05.2025 Volume 4 Issue 5 View more Download
PATHOPHYSIOLOGY OF AUTOIMMUNE DISEASES MECHANISMS OF IMMUNE TOLERANCE DISRUPTION

This article explores the complex pathophysiology of autoimmune diseases with a primary focus on the mechanisms underlying the breakdown of immune tolerance. Immune tolerance is essential for preventing the immune system from attacking the body’s own tissues. The review covers both central and peripheral tolerance processes, highlighting how genetic predispositions, environmental factors, and immune regulatory failures contribute to the development of autoimmunity. Key cellular players, such as regulatory T cells and antigen-presenting cells, are discussed in relation to their roles in maintaining immune homeostasis. Additionally, the article examines current understanding of molecular mimicry, epitope spreading, and other pathogenic mechanisms leading to self-reactivity. The challenges in diagnosis and treatment of autoimmune diseases are also addressed, emphasizing the need for targeted therapeutic approaches aimed at restoring immune tolerance rather than merely suppressing immune responses.


20.05.2025 Volume 4 Issue 5 View more Download
BIOPARCHALANUVCHI PLYONKALAR ISHLAB CHIQARISH VA ULARNING QO’LLANILISH YO’NALISHLARI

Hozirgi vaqtda polimer chiqindilar ko’payib atrof muhitga katta zarar keltiryapti. Shuning uchun ularni kamaytirish ularning o’rniga tabiiy polimerlar olish dolzarb hisoblanadi. Bunday tabiiy polimerlar turli xil agressiv muhitda parchalanib ketadi. Bunday bioparchalanuvchi polimerlar an’anaviy polimerlarga qaraganda ancha qimmatroqdir. Arzonroq bioparchalanuvchi polimerlar olish uchun polimer kompozitlardan foydalanish bilan bog’liq bo’ladi.


20.05.2025 Volume 4 Issue 5 View more Download
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