Mazkur maqolada Oʻzbekiston Davlat yozuvchisi, adabiyot xazinasi boʻlmish Abdulla Qahhorning “Bemor” hikoyasi oldingi davr va hozirgi davr talqini. Shu bilan birga asardagi bosh qahramon va boshqa salbiy obrazlar tasvirlangan.

Mazkur maqolada Shayboniylar davlati (1500–1599) davridagi ijtimoiy tuzilma va davlat tomonidan amalga oshirilgan islohotlar tarixiy manbalar asosida tahlil qilinadi. Jamiyatning asosiy qatlamlari – hukmdorlar, diniy ulamolar, harbiylar, dehqonlar va savdogarlar o‘rtasidagi o‘zaro munosabatlar, ularning davlat boshqaruvidagi o‘rni va vazifalari yoritiladi. Shuningdek, ma’muriy, harbiy, yer-soliq va diniy sohalarda olib borilgan islohotlar mazmuni hamda ularning jamiyat barqarorligiga ta’siri ochib beriladi. Maqola ijtimoiy taraqqiyotga ta’sir etgan tarixiy omillarni chuqur anglashga xizmat qiladi.

This article explores the complex pathophysiological mechanisms underlying the development of kidney failure. It highlights the key roles of hemodynamic changes, cellular injury, inflammation, oxidative stress, and hormonal imbalances in the progression of renal dysfunction. The chronic activation of the renin-angiotensin-aldosterone system and its contribution to fibrosis and nephron loss are discussed in detail. The article also examines how inflammatory processes and oxidative damage exacerbate kidney tissue injury, while hormonal disturbances contribute to systemic complications such as anemia and mineral imbalance. Emphasis is placed on the importance of early detection and targeted treatment strategies to slow disease progression and improve patient outcomes. The review concludes with a discussion on future research directions aimed at developing novel diagnostic markers and therapeutic approaches for kidney failure.

Psixologiyalıq másláhát degen ne, ol qanday, shólkemlestiriliwi hám alıp barılıwı haqqındaǵı tiykarǵı, keń kólemli hám túsinikli bayanlanǵan maǵlıwmatlar haqqında túsinik berilgen.

This article explores the pathophysiological mechanisms underlying the development of hypertension, with a special emphasis on the hormonal factors that contribute to elevated blood pressure. Hypertension, one of the most prevalent cardiovascular disorders worldwide, results from a complex interplay between genetic predisposition, environmental influences, and dysregulation of multiple physiological systems. The article discusses how alterations in renal function, vascular resistance, and sympathetic nervous system activity lead to chronic elevation of arterial pressure. Particular attention is given to the renin-angiotensin-aldosterone system (RAAS), vasopressin, and other endocrine factors such as catecholamines and natriuretic peptides. The review also highlights the feedback loops and receptor sensitivities that sustain hypertensive states over time. Understanding these hormonal contributions is essential for identifying therapeutic targets and improving the management of hypertensive patients. Overall, the paper aims to provide a comprehensive view of how hormonal imbalance acts as a key driver in the pathogenesis of hypertension.