This article explores the pathophysiological mechanisms underlying the development of hypertension, with a special emphasis on the hormonal factors that contribute to elevated blood pressure. Hypertension, one of the most prevalent cardiovascular disorders worldwide, results from a complex interplay between genetic predisposition, environmental influences, and dysregulation of multiple physiological systems. The article discusses how alterations in renal function, vascular resistance, and sympathetic nervous system activity lead to chronic elevation of arterial pressure. Particular attention is given to the renin-angiotensin-aldosterone system (RAAS), vasopressin, and other endocrine factors such as catecholamines and natriuretic peptides. The review also highlights the feedback loops and receptor sensitivities that sustain hypertensive states over time. Understanding these hormonal contributions is essential for identifying therapeutic targets and improving the management of hypertensive patients. Overall, the paper aims to provide a comprehensive view of how hormonal imbalance acts as a key driver in the pathogenesis of hypertension.

Дaннaя cтaтья paccмaтpивaет ocoбеннocти пеpевoдa pеaлий в кoнтекcте худoжеcтвеннoгo текcтa нa мaтеpиaле пеpевoдa пoэм узбекcкoгo пoэтa Мaкcудa Шейхзaде. В cтaтье aнaлизиpуютcя paзличные типы pеaлий, вcтpечaющиеcя в пoэзии Шейхзaде, и пpедлaгaютcя cтpaтегии их aдеквaтнoгo пеpевoдa, c учетoм coхpaнения культуpнoй cпецифики opигинaлa и oбеcпечения дocтупнocти текcтa для читaтеля-инoфoнa.

Bul maqalada emocional sharshaw sindromı (burnout) túsinigi, onıń qáliplesiw sebepleri hám ásirese, sociallıq belsendilik penen baylanıslı júzege keletuǵın psixologiyalıq hám fiziologiyalıq qáwip-qáterler tallanǵan. Sonday-aq, sindromnıń aldın alıw boyınsha usınıslar da berilgen.

This theoretical research explores the economic views of Abdurauf Fitrat, a prominent Central Asian thinker, by comparing them with his contemporaries and interpreting them through a modern lens. Fitrat's ideas reflect a synthesis of Islamic economic principles and modernist thought. By conducting a comparative analysis with regional and global economic thinkers of his time, this paper aims to highlight the unique aspects of his vision. The study uses a descriptive-analytical method and draws on primary texts, archival material, and secondary scholarly interpretations.

Ushbu maqolada XIX asr oxiri va XX asr boshlarida O‘rta Osiyoda yuzaga kelgan jadidchilik harakatining mazmun-mohiyati, tarixiy bosqichlari, asosiy g‘oyalari hamda bugungi kunda bu harakat merosining O‘zbekiston jamiyatidagi ahamiyati tahlil qilinadi. Jadidchilik harakatining asoschilari tomonidan ilgari surilgan ma’rifiy, ijtimoiy va siyosiy g‘oyalarning zamonaviy ta’lim tizimi, gender tengligi, milliy o‘zlikni anglash va fuqarolik jamiyati qurilishiga ta’siri yoritilgan. Shuningdek, jadid matbuoti, teatr va adabiy merosining yosh avlod tarbiyasidagi roli, bugungi islohotlar bilan o‘zaro bog‘liqligi chuqur o‘rganilgan. Maqolada tarixiy va zamonaviy qarashlar uyg‘unligi orqali jadidchilik harakatining dolzarbligi va bugungi kundagi o‘rni ilmiy asosda tahlil etiladi.