Qalqonsimon bez xiqildoq qalqonsimon tog’ayi ustida, bo’yinning oldingi yuzasida joylashgan. Qalqonsimon bez bo’yincha bilan birikkan 2 bo’lakdan iborat. Massasi taxminan 30 gr keladi. Qalqonsimon bez tiroksin gormoni ishlab chiqaradi. Tiroksin tarkibiga yod kirib, u qalqonsimon bezga tashqaridan (bu yerga qon oqimi bilan keltiriladi), oziq-ovqat mahsulotlari va ichimlik suvdan tushadi. Qalqonsimon bez moddalar almashinuviga ta’sir qiladi: normaga nisbatan ko’p miqdorda tiroksin ishlab chiqarilishi modda almashinuvining normal bo’lmagan oshib ketishiga olib keladi. Qalqonsimon bez funksiyasi pasayib ketganda va bu gormon yetarlicha ishlanmaganda, aksincha, moddalar almashinuvi pasayadi.

Onkologiya sohasida saratonni erta aniqlash muhim ahamiyatga ega, chunki erta aniqlangan holatlar davolash imkoniyatlarini sezilarli darajada oshiradi. Ushbu jarayonda bir qator usullar qo‘llaniladi, jumladan, profilaktik tekshiruvlar va skreening. Qon tahlillari va genomik testlar orqali saratonga oid biomarkerlar aniqlanadi. Ultrasonografiya, magnit-rezonans tomografiya (MRT) va kompyuter tomografiyasi (KT) kabi imaging usullari yordamida ichki organlardagi o‘zgarishlar kuzatiladi. Simptomlar, masalan, og‘riq va massalarning o‘zgarishi ham diqqatga sazovor. Oila tarixi va genetik predispozitsiya ham e’tiborga olinishi zarur. Barcha ushbu usullar oʻzaro birlashib, onkologlar va sog‘liqni saqlash mutaxassislari tomonidan samarali tasdiqlash va davolash strategiyalarini amalga oshirishga yordam beradi.

Ushbu maqolada buyuk mutafakkir va shoir Hazrat Alisher Navoiy ijodida ilm olishning o‘rni va ahamiyati tahlil qilinadi. Shoir asarlarida ilmga bo‘lgan rag‘bat, ma’rifatning insoniy va ijtimoiy hayotdagi o‘rni, bilimsizlikning salbiy oqibatlari yoritilgan.

Menopause is a critical transitional phase in a woman’s life characterized by the cessation of ovarian function and the end of menstruation. It is often accompanied by a range of physical, emotional, and metabolic symptoms that vary in intensity and duration. Recent research indicates that vitamin D plays a significant role not only in bone metabolism but also in the modulation of menopausal symptoms. The aim of this study was to investigate the features of the menopausal course in women diagnosed with vitamin D deficiency and determine how hypovitaminosis D influences the severity of menopausal manifestations. The study revealed a notable correlation between low serum levels of vitamin D and the severity of vasomotor symptoms, mood disorders, sleep disturbances, and musculoskeletal pain. This research underlines the importance of monitoring and correcting vitamin D levels in peri- and postmenopausal women to reduce symptom burden and improve overall quality of life. The menopausal period represents a pivotal phase in the physiological aging process of women, characterized by profound hormonal, psychological, and metabolic transitions. Beyond the well-documented decline in estrogen levels, micronutrient imbalances—particularly vitamin D deficiency—have emerged as critical modifiers of menopausal health outcomes. This study explores the intricate interplay between hypovitaminosis D and the clinical progression of menopause, focusing on symptom intensity, systemic complications, and quality of life implications. The investigation, conducted on a representative cohort of postmenopausal women, revealed a significant amplification of menopausal discomfort in individuals with deficient serum vitamin D levels. Notably, manifestations such as thermal dysregulation, cognitive disturbances, emotional instability, and skeletal complaints were disproportionately prevalent in this subgroup. These findings suggest a potential therapeutic target in vitamin D optimization to mitigate the climacteric burden and promote healthier aging trajectories among menopausal populations.

Ушбу мақола олий таълим институтлари, академик лицей ва коллежлар ҳамда умумтаълим мактабларида матншунослик ва адабий манбушунослик алоқадор фанлар ўқитувчилари ва адабиётга қизиққан ҳар бир киши учун ХVII асрнинг иккинчи ярмида Тошкентда таваллуд топган маш¬ҳур файласуф шоир ва мутасаввуф олим-Мавлоно Хароботий ҳақида, унинг бизгача етиб келган “Куллиёт”, “Маснавийи Хароботий” ва “Рисолаи фақрийя” асарларида шариатнинг фиқҳга оид масалалари, тасаввуфнинг асосий қоидалари, одоб-ахлоқ ҳамда ҳаётга нисбатан бўлган фалсафий муносабатлари маснавий усулида баён этилгани ва комил инсонни тарбиялаш йўлидаги аҳамияти ҳақида маълумот беради.