Maqolada 2022–2024 yillarda Respublika perinatal markazida tug‘ruq qilgan yosh onalarda homiladorlik va tug‘ruq jarayonining xususiyatlari o‘rganish natijalari keltirilgan. O‘smir yoshdagi ayollar guruhida homiladorlik asoratlari statistik jihatdan ancha tez-tez uchrashi aniqlangan. Anemiya, platsenta bilan bog‘liq buzilishlar kabi patologiyalarda statistik ahamiyatli farq kuzatilgan. O‘smirlikdagi homiladorlik xavfli asorat — preeklampsiya rivojlanishiga olib kelishi mumkin. Yosh homiladorlarda vaqtidan oldin tug`ruq xavfi yuqori bo‘lgan guruhga kiradi. O‘smirlar guruhida kesarcha kesish yo‘li bilan tug‘ruq qilish holatlari tahlili keltirilgan. Olingan ma’lumotlar yosh onalarda homiladorlik va tug‘ruq asoratlarini oldini olish choralari ishlab chiqish va amaliyotga joriy etish uchun asos bo‘ladi.

Ischemic stroke in young patients is an important cerebrovascular condition associated with a combination of clinical, metabolic, immunological, and genetic risk factors. The development of stroke at a young age may be influenced by hypertension, obesity, dyslipidemia, impaired glucose metabolism, smoking, physical inactivity, cardiovascular disorders, inflammatory processes, and hereditary predisposition. The aim of this study was to assess the main clinical, metabolic, and immunogenetic factors associated with ischemic stroke in young patients and to emphasize the importance of their comprehensive evaluation. Particular attention was given to neurological manifestations, blood pressure, body mass index, lipid profile, glucose metabolism, inflammatory markers, thrombophilic factors, and genetic predisposition. The analysis showed that the interaction of several risk factors may contribute to vascular endothelial dysfunction, thrombosis, and cerebrovascular injury. Immunological and genetic factors may be particularly relevant in young patients when conventional cardiovascular risk factors do not fully explain the development of stroke. Early identification of modifiable risk factors and appropriate assessment of immunological and genetic characteristics may improve individual risk stratification.

The article discusses the artistic-publicistic synthesis of historical events, mythological legends, and ethnographic materials in M. Nizanov's novel-essay "The Karakalpaks". The portrayal of the origin (ethnogenesis) of the Karakalpak people, the history of their statehood, their religious-spiritual worldview, and their diplomatic relations with the Russian Empire are evaluated from a scientific-critical perspective. It explores the author's masterful utilization of historical sources (archive documents, genealogical records) and examples of oral literature (legends, epics) within the framework of the "novel-essay" genre, as well as the work's role in restoring the national mentality and historical memory of the Karakalpak people.

This article examines the mechanisms by which alkaloids influence the cardiovascular system and evaluates their major pharmacological effects. Alkaloids are naturally occurring nitrogen-containing compounds with diverse biological activities and significant pharmacological potential. The study focuses on their effects on cardiac rhythm, myocardial contractility, cardiac conduction, vascular tone, and arterial blood pressure. Particular attention is given to the interaction of alkaloids with ion channels, adrenergic and cholinergic receptors, the autonomic nervous system, and intracellular signaling pathways. The analysis indicates that different alkaloids may produce vasodilatory or vasoconstrictive effects and may modify heart rate and myocardial contractility depending on their chemical structure, concentration, and mechanism of action. The potential therapeutic significance of alkaloids in cardiovascular pharmacology is also considered, together with their possible toxic effects and dose-dependent adverse reactions. The findings suggest that alkaloids represent an important source of biologically active compounds with potential applications in cardiovascular drug development. Further experimental and clinical studies are required to establish their therapeutic efficacy, optimal dosage, pharmacokinetic characteristics, and long-term safety.

Ushbu maqolada o‘qituvchi tomonidan o‘quvchilarga ko‘rsatiladigan ijtimoiy, emotsional va akademik qo‘llab-quvvatlashning o‘quvchilarning psixologik farovonligi bilan o‘zaro bog‘liqligi pedagogik-psixologik nuqtayi nazardan tahlil qilinadi. Maqolada o‘qituvchi qo‘llab-quvvatlashining mazmuni, uning asosiy shakllari hamda psixologik farovonlikning tarkibiy komponentlari yoritiladi. O‘zbek va xorijiy ilmiy manbalar tahlili asosida o‘qituvchining empatik munosabati, o‘quvchi fikrini hurmat qilishi, konstruktiv fikr-mulohaza berishi, akademik qiyinchiliklarda yordam ko‘rsatishi va psixologik xavfsiz ta’lim muhitini yaratishi o‘quvchilarning farovonligi bilan bog‘liq muhim omillar ekanligi asoslanadi.