Call-Fleming syndrome, or reversible cerebral vasoconstriction syndrome (RCVS), is a clinico-radiological syndrome characterized by thunderclap headache, segmental or multifocal narrowing of the intracranial arteries, and their regression over time [1–4]. In practice, diagnosis is often delayed because of the polymorphic clinical course of the syndrome, its similarity to other cerebrovascular and headache syndromes, and the fact that early neuroimaging does not always provide clear confirmation [4–6]. The aim of this study was to evaluate clinical-neurological signs, trigger factors, neuroimaging and paraclinical findings, conformity with diagnostic criteria, and outcomes of clinical management in patients with Call-Fleming syndrome. The study was conducted as a prospective, single-center, observational cohort. Between 2023 and 2025, 30 patients diagnosed with or clinically suspected of having Call-Fleming syndrome were followed in the 1st and 2nd Neurology Departments of the Andijan State Medical Institute Clinic. The results showed that 76.7% of patients were women, and postpartum cases accounted for 30.0%. Thunderclap headache occurred in 96.7% of cases, segmental or multifocal vasoconstriction in 80.0% of patients, and reversibility was documented in 73.3%. Among trigger factors, vasoactive/serotonergic drugs (40.0%) and postpartum/hormonal factors (30.0%) were predominant. Full conformity with diagnostic criteria was found in 70.0%, partial conformity in 20.0%, and suspected cases accounted for 10.0%. Conservative treatment based on nimodipine predominated, and overall complete clinical regression was recorded in 66.7% of patients [15–18]. These findings indicate that targeted identification of triggers, detection of vasoconstriction using MRA/CTA, and dynamic follow-up are crucial for the early diagnosis of Call-Fleming syndrome.

Ushbu maqolada Orol bo‘yi hududining murakkab ekologik sharoitlari va ularning dental implantatlarning suyak to‘qimalariga integratsiya jarayoniga ko‘rsatadigan ta’siri tahlil qilingan. Hududdagi sho‘rlanish darajasi, chang-tuz aerozollari, ichimlik suvi tarkibi va umumiy ekologik stress omillari organizmning mineral almashinuviga, suyak regeneratsiyasi va implant atrofidagi to‘qimalarning biologik javobiga sezilarli darajada ta’sir ko‘rsatishi yoritilgan. Shuningdek, implantologik jarayonlarda yuzaga keladigan biologik moslashuv va muvaffaqiyat darajasiga ekologik sharoitlarning bilvosita ta’siri ilmiy asosda ko‘rib chiqilgan.

Ushbu maqolada psixosomatik kasalliklarning kelib chiqish sabablari, ularning shakllanish jarayonlari hamda kasalliklarning paydo bo‘lishida psixologik omillarning o‘rni ilmiy-nazariy jihatdan tahlil qilinadi. Psixosomatika inson ruhiy holati bilan jismoniy salomatligi o‘rtasidagi o‘zaro bog‘liqlikni o‘rganadigan muhim ilmiy yo‘nalishlardan biri hisoblanadi. Maqolada psixosomatika fanining shakllanishi, rivojlanish bosqichlari hamda uning tibbiyot va psixologiya fanlari bilan o‘zaro aloqadorligi keng yoritib beriladi. Shuningdek, psixosomatik kasalliklarning paydo bo‘lishiga ta’sir qiluvchi stress, ichki ziddiyatlar, ruhiy zo‘riqish, emotsional bosim kabi omillar ilmiy manbalar asosida tahlil qilinadi. Tadqiqot davomida psixosomatik kasalliklarning shakllanish mexanizmlari, ularning inson organizmida qanday namoyon bo‘lishi hamda psixologik jarayonlar bilan bog‘liq jihatlari ochib beriladi. Ayniqsa, insonning uzoq davom etuvchi ruhiy zo‘riqishi, tashvish, qo‘rquv va ichki ziddiyatlari turli jismoniy kasalliklarning yuzaga kelishiga sabab bo‘lishi mumkinligi ilmiy dalillar asosida ko‘rsatib o‘tiladi. Maqolada psixosomatik kasalliklar bilan ayrim nevrologik kasalliklar o‘rtasidagi o‘xshash va farqli jihatlar ham tahlil qilinadi. Shuningdek, psixosomatika fanining rivojlanishida mashhur psixoanalitik olim Sigmund Freud tomonidan ilgari surilgan nazariy qarashlarning ahamiyati alohida yoritiladi. Uning inson ruhiy jarayonlari va ichki kechinmalari jismoniy salomatlikka ta’sir ko‘rsatishi haqidagi g‘oyalari keyingi ilmiy tadqiqotlar rivojiga muhim turtki bo‘lgan. Mazkur maqolada psixosomatik kasalliklarni o‘rganishda zamonaviy psixologik yondashuvlar hamda ularni oldini olish va davolash jarayonida psixologik yordamning ahamiyati ham ko‘rib chiqiladi.

Mazkur maqolada global pandemiyalardan keyingi davrda profilaktik tibbiyotning ahamiyati, uning asosiy yo‘nalishlari hamda sog‘liqni saqlash tizimidagi o‘rni yoritilgan. Pandemiya tajriba asosida kasalliklarni oldini olish, erta aniqlash va aholi salomatligini mustahkamlashning ustuvor vazifalari tahlil qilingan.

В статье рассматриваются вопросы обеспечения информационной безопасности в нотариальной практике. Особое внимание уделяется правовым, техническим и организационным мерам защиты конфиденциальной информации, а также оценке рисков утечки данных и возможных нарушений безопасности. Анализируются современные цифровые технологии, применяемые для защиты информации, включая системы шифрования, двухфакторную аутентификацию, защищённые каналы передачи данных и резервное копирование. Также рассматривается практика обучения персонала нотариальных учреждений по вопросам информационной безопасности и внедрение новых технологий для повышения эффективности работы. Статья содержит рекомендации по комплексной защите информации, снижению рисков несанкционированного доступа и повышению доверия клиентов к нотариальным услугам.