The development of primary open-angle glaucoma (POAG) is currently considered to be a chain of interaction between etiological and pathogenetic factors, among which the leading role is played by genetic predisposition, general changes, ischemia, primary local functional and dystrophic changes, disturbances in hydrostatics and hydrodynamics of the eye, increased intraocular pressure, vascular disorders, dystrophy and tissue degeneration. Purpose. The purpose of this study is to study the factors of endothelial dysfunction leading to a decrease in ocular hemoperfusion in patients with primary open-angle glaucoma. Methods. The study included 92 patients with POAG, aged 65 to 80 years. The level of lipid peroxidation and AOS, the lipid composition of the blood and the indicators of the complement system were studied before and after treatment. Conclusion. The study of indicators of oxidative stress and antioxidant status of blood serum according to the corresponding levels (high, medium and low) makes it possible to determine the risk of disease progression and evaluate the effectiveness of treatment in patients with POAG.

Translation studies have evolved significantly in higher education, with methodologies that bridge theoretical foundations and practical applications. This article explores the dominant teaching methodologies in translation programs, emphasizing their importance in developing competent and versatile translators. These methods include task-based learning, translation workshops, contrastive analysis, project-based learning, technology integration, genre-specific training, and the use of corpus linguistics. By examining each approach, the article sheds light on how institutions prepare students for the complexities of translation in professional contexts.

Today, the increase in the number of the population and the increase in the demand for food products in our Republic, obtaining a high yield at low cost and achieving economic efficiency, as well as providing the population with enough food products, early, fertile, and external stress factors in cotton cultivation. , the development of agrotechnologies of treatment with new growth regulators in the cultivation of high and quality fiber resistant to diseases and pests is one of the urgent issues. On this basis, it is also important to carry out scientific research on the development of optimal norms and terms for the use of new growth regulators in the care of agricultural crops.

The article reviews current trends in multi-word lexeme processing in computational linguistics, emphasizing the importance of effective natural language analysis. Key areas include: Deep learning: Using neural networks to automatically extract features from texts and work with large amounts of data. Semantic models: Using word vector representations to improve the accuracy of analysis and understand semantic relationships. Multilingual systems: Developing technologies that provide high-quality analysis and translation of texts in different languages. Big data processing: Creating methods for fast and efficient processing of arrays of text information. Integration with other areas: Combining computational linguistics technologies with image and sound processing for complex analysis. The article also highlights the contributions of renowned researchers such as Noam Chomsky and Karen Spark Johnson to the development of this field. Particular attention is paid to the benefits of multi-word lexeme processing for Turkic languages, including taking into account morphological complexity, resolving ambiguities, and improving the quality of machine translation. The work emphasizes the importance of this area for the development of language technologies and communication in the Turkic language community.

This article discusses the services provided in the tax system through information technologies, their types, interactive services in the tax system and their importance, benefits to legal entities and individuals, and their role in improving the state budget. Today, information technologies are becoming important for providing convenient and fast service to taxpayers, improving the activities of tax authorities and reducing errors. The article provides detailed information about the services provided with the help of these technologies, their positive impact on taxpayers and the activities of tax authorities. Among the information technology services used in the tax system, online tax declaration submission, electronic invoicing system, personal office of taxpayers and other interactive services are distinguished. These technologies allow tax authorities to receive and process information in real time, while saving time and money for taxpayers. The article also discusses the effectiveness of information technology services, the possibilities of paperless work through them, and issues of data security.