The article about the role of vascular wall stiffness in the development of coronary heart disease and renal dysfunction. At the beginning of the review, the definition of the stiffness of the vascular wall is given. Rigidity of the aorta and large vessels of the elastic type is being studied as an independent marker of the risk of developing coronary artery disease and how its measurement allows a more accurate assessment of the prognosis of the disease Methods for noninvasive determination of vascular stiffness by pulse wave propagation velocity, central pulse pressure level, and index of pulse pressure increase in the aorta allows to define formation of high-risk groups for the purpose of its further correction.

Во многих клинико-экспериментальных исследованиях доказано прямое участие иммуно-воспалительных факторов в течении ХСН и развитии неблагоприятных последствий. Несмотря на то, что некоторые исследования показали, что уровни эндотоксинемии и цитокинемии различаются при гемодинамических фенотипах ХСН, влияние этих процессов на течение ХСН с сохраненной и промежуточной фракциями выброса остаются неизученными.

Maqolada turkiy xalqlarning dostonlari va afsonalari asosida turkiy xalqlar mifologiyasi tahlil qilindi. “Qo’rqut ota” kabi boshqa bir qator turkiy xalqlar dostonlaridan keng foydalanildi.

Ushbu maqolada innovatsion iqtisodiyot sharoitida davlatning ijtimoiy siyosatini rivojlantirish masalalari chuqur tahlil qilinadi. Innovatsion iqtisodiyotning asosiy xususiyatlari – texnologik taraqqiyot, raqamli transformatsiya, ilm-fan va inson kapitaliga asoslangan rivojlanish jarayonlari davlatning ijtimoiy siyosatini yangilash zaruratini keltirib chiqaradi. Davlat siyosati jamiyatdagi ijtimoiy tengsizlikni kamaytirish, aholining turmush darajasini oshirish va ijtimoiy himoyani kuchaytirishga yo‘naltirilishi lozim.

Ischemic heart disease is one of the main causes of disability and death among the population all over the world, including in Uzbekistan. Among the comorbid conditions observed in this group of patients, kidney dysfunction is of particular importance, and even the earliest subclinical disorder affects the exacerbation of the main disease and the development of complications, as well as mortality rates as an independent risk factor. This article aims to investigate the significance of creatinine, cystatin C, proteinuria and podocyturia in early diagnosis of RD in patients with stable angina pectoris and their association with cardiovascular risk. Cystatin C has been reported to be reliably effective compared to serum creatinine in the early diagnosis of RD in patients with stable angina pectoris. It has also been confirmed that podocyturia is one of the main markers for its early detection and assessment of its progression.