This scientific paper explores the general pathophysiological mechanisms of inflammation, a fundamental biological response to harmful stimuli such as infection, injury, or immune dysregulation. The study provides a comprehensive overview of the key stages of inflammation, including initiation, amplification, and resolution, as well as the complex cellular and molecular components involved. Special emphasis is placed on immune cells such as macrophages, neutrophils, and lymphocytes, along with inflammatory mediators including cytokines, chemokines, prostaglandins, and nitric oxide. The work distinguishes between acute and chronic inflammation, explaining their unique features, triggers, and pathological consequences. Disruption in this process is highlighted as a major contributor to long-term inflammatory conditions such as autoimmune disorders, cardiovascular disease, and cancer. Clinical implications, diagnostic markers, and therapeutic strategies targeting specific pathways of inflammation are also addressed. This research is intended to serve as a valuable resource for students of medical and biological sciences, healthcare professionals, and researchers interested in immunology and disease mechanisms.

Mazkur maqolada inklyuziv ta’lim sohasidagi xalqaro, milliy va hududiy o‘zgarishlar, global tendensiyalar, milliy strategiyalar va joylardagi amaliyotlar tahlil qilinadi. Inklyuziv ta’limga oid ilg‘or tajribalar, yondashuvlar hamda pedagogik ta’limning zamonaviy yo‘nalishlari oʻrganiladi. Shuningdek, alohida ta’lim ehtiyojlariga ega bolalarning sifatli ta’lim olishiga oid imkoniyatlarni kengaytirish va barqaror rivojlanish maqsadlarida inklyuziv yondashuvlarning roli tahlil qilinadi. Maqolada ilmiy-nazariy asoslar bilan bir qatorda real misollar va statistik ma’lumotlarga tayanilgan.

This article examines the role of speech acts in the development of pragmatic competence among EFL (English as a Foreign Language) learners, with a specific focus on how language conveys social meaning. It explores how explicit instruction in requests, refusals, apologies, and other speech acts can improve learners' ability to communicate appropriately across cultural and situational contexts. The study argues for the inclusion of pragmatic elements in language teaching as a means of promoting authentic, socially aware communication.

В статье рассматриваются особенности методики преподавания японского языка в условиях многоязычной образовательной среды на примере Республики Узбекистан. Учитывая лингвистическое разнообразие обучающихся, владеющих узбекским, русским и английским языками, автор анализирует влияние языкового опыта на усвоение японского языка, выделяя как положительные, так и отрицательные аспекты межъязыкового переноса. Особое внимание уделяется интегрированному языковому подходу, роли английского языка как языка-посредника, а также необходимости включения культурных компонентов в учебный процесс. Подчёркивается значение цифровых технологий и мультиязычных ресурсов в повышении мотивации и эффективности обучения.

Bul maqalada qaraqalpaq kompozitor hám namagerlerdiń bir qansha jazǵan qosıqlarınıń atları haqqında aytıp ótilgen. Bunnan basqa Keńesbay Abdulaev qálemine tiyisli bolǵan «Elim bar» hám «Bizge kel» qosıǵı boyınsha tolıq talıqlaw berilgen.