Emocional sharshaw - bul uzaq dawam etken stress, emocional hám fizikalıq artıqsha júklemeler nátiyjesinde insannıń ruwxiy resurslarınıń tawsılıwı hám sharshaw jaģdayı. Bul maqalada sezimlik sharshawdıń aqıbetleri hám onıń insan organizmine bolǵan qáwip-qáterleri tallanǵan. Maqalada sezimlik sharshawdıń psixologiyalıq, fizikalıq, sociallıq hám kásiplik tarawlardaǵı unamsız tásirleri hám olardı azaytıwdıń nátiyjeli usılları sáwlelendirilgen. Maqala sezimlik sharshawdıń uzaq múddetli aqıbetlerinen saqlanıw hám olardı saplastırıw boyınsha usınıslardı usınadı.

В статье рассмотрен сновные трудности и стратегии перевода реалий в контексте художественного текста (на материале перевода поэм Максуда Шейхзаде), а также даны определения термина реалия.В статье рассмотрен сновные трудности и стратегии перевода реалий в контексте художественного текста (на материале перевода поэм Максуда Шейхзаде), а также даны определения термина реалия.

Bul maqalada emocional sharshaw sindromı (burnout) túsinigi, onıń qáliplesiw sebepleri hám ásirese, sociallıq belsendilik penen baylanıslı júzege keletuǵın psixologiyalıq hám fiziologiyalıq qáwip-qáterler tallanǵan. Sonday-aq, sindromnıń aldın alıw boyınsha usınıslar da berilgen.

This article explores the complex pathophysiology of autoimmune diseases with a primary focus on the mechanisms underlying the breakdown of immune tolerance. Immune tolerance is essential for preventing the immune system from attacking the body’s own tissues. The review covers both central and peripheral tolerance processes, highlighting how genetic predispositions, environmental factors, and immune regulatory failures contribute to the development of autoimmunity. Key cellular players, such as regulatory T cells and antigen-presenting cells, are discussed in relation to their roles in maintaining immune homeostasis. Additionally, the article examines current understanding of molecular mimicry, epitope spreading, and other pathogenic mechanisms leading to self-reactivity. The challenges in diagnosis and treatment of autoimmune diseases are also addressed, emphasizing the need for targeted therapeutic approaches aimed at restoring immune tolerance rather than merely suppressing immune responses.

Mazkur maqola, toshkent viloyаti xаlq xo‘jаligidа temir yo‘llаr tizimining o‘rni mavzusida yozilgan. Ushbu maqolada, toshkent viloyаti xаlq xo‘jаligidа temir yo‘llаr tizimining o‘rni va xususiyatlari o‘rganilgan. Maqolada toshkent viloyаti xаlq xo‘jаligidа temir yo‘llаr tizimining o‘rni samarali bo‘lishi va ularning yuqori natijalarga erishishi uchun qanday shart-sharoitlar zarurligi tahlil qilingan.