Pulmonary tuberculosis (TB) remains a major global health challenge, particularly in low- and middle-income countries. Despite the effectiveness of standard anti-tubercular therapy (ATT), limitations such as drug resistance, long treatment duration, toxicity, and poor patient compliance necessitate alternative or complementary therapeutic strategies. Herbal medicine, a cornerstone of traditional medicine systems, has emerged as a promising adjunct in TB management. This review explores the pharmacological potential of medicinal plants with antimycobacterial, immunomodulatory, and anti-inflammatory properties. Key herbs, their active constituents, and mechanisms of action are discussed. Integration of herbal medicine in TB treatment may enhance therapeutic efficacy, reduce adverse effects, and improve patient outcomes, though more clinical trials are required to validate efficacy and safety.

The automatization of the heart is its fundamental ability to independently generate electrical impulses that initiate heart contractions, without external stimulation from the nervous system. This review is devoted to a comprehensive review of this phenomenon. The main driver of the rhythm is normally the sinoatrial (CA) node, whose cells have unique electrophysiological properties, in particular, the ability to slow spontaneous diastolic depolarization (phase 4 of the action potential). This process is based on the complex dynamics of ion currents, including the "funny" current (If), calcium currents (ICa,T, ICa,L) and potassium currents (IK). The review examines in detail the ionic mechanisms of pacemaker activity, the hierarchy of pacemakers (CA node, atrioventricular node, Gis-Purkinje system) and the phenomenon of suppression of the underlying centers of automatism (overdrive suppression). The mechanisms of regulation of heart rate by the autonomic nervous system (sympathetic and parasympathetic), humoral factors (adrenaline, thyroid hormones) and other influences (temperature, ion balance, hypoxia) are highlighted. The clinical significance of automation is discussed, including pathological conditions such as CA node dysfunction (sinus node weakness syndrome), ectopic foci of automatism, atrial and ventricular arrhythmias associated with abnormal automation, as well as approaches to their diagnosis (ECG) and treatment (antiarrhythmic drugs, artificial pacemakers). In conclusion, modern research directions in this field are considered, including the study of the genetic basis of automatism disorders and the development of biological rhythm drivers.

Bul maqalada Qaraqalpaq jazıwshısı K.Karimovtıń “Aǵabiy” romanında Antonim ham sinonim sózlerdiń qollanılıw ózgeshelikleri berilgen. Jazıwshınıń romanda antonim ham sinonim sózlerdi qollanıw stili, ózgeshelikleri mısallar tiykarında talqılanǵan.

Mazkur maqolada o‘zbek tilidagi gul nomlari va ularni ifoda etuvchi so‘zlarning semantik xususiyatlari o‘rganiladi. Leksik-semantik tahlil asosida gul nomlarining milliy-madaniy xususiyatlari, obrazlilik darajasi hamda ularning metaforik va poetik ma’noda qo‘llanish holatlari yoritiladi. Mumtoz adabiyotda, ayniqsa Alisher Navoiy she’riyatida, gul obrazining poetik, ramziy va semantik jihatdan teran qo‘llanishi kuzatiladi. Shu sababli gul nomlarini faqat botanik terminlar sifatida emas, balki semantik struktura, poetik timsol, va lingvokulturologik birlik sifatida tadqiq qilish muhimdir. Shuningdek, turli adabiy manbalarda gul nomlarining sinonim, antonim, metafora va metonimiya kabi usullar bilan qanday ifodalangani tahlil qilinadi.

Ushbu maqolada atov gaplarning ma’nosi, shakllanishi va maktab darsliklarida ularning qo‘llanilish usullari o‘rganildi. Atov gaplar nutqni yanada jonlantirish, ta’sirchanlikni oshirish va mavzuni aniq ifodalashda muhim vosita hisoblanadi. Tadqiqotda atov gaplarning turli turlari tahlil qilinib, ularni o‘quvchilarga samarali o‘rgatish metodikalari ko‘rib chiqildi. Mashqlar yordamida atov gaplarni to‘g‘ri qo‘llash usullari va darsliklardagi misollar tahlil qilindi. Natijalar atov gaplarni o‘rgatish jarayonini takomillashtirishga xizmat qilishi mumkin.