GENERAL PATHOPHYSIOLOGICAL MECHANISMS OF INFLAMMATION

This scientific paper explores the general pathophysiological mechanisms of inflammation, a fundamental biological response to harmful stimuli such as infection, injury, or immune dysregulation. The study provides a comprehensive overview of the key stages of inflammation, including initiation, amplification, and resolution, as well as the complex cellular and molecular components involved. Special emphasis is placed on immune cells such as macrophages, neutrophils, and lymphocytes, along with inflammatory mediators including cytokines, chemokines, prostaglandins, and nitric oxide. The work distinguishes between acute and chronic inflammation, explaining their unique features, triggers, and pathological consequences. Disruption in this process is highlighted as a major contributor to long-term inflammatory conditions such as autoimmune disorders, cardiovascular disease, and cancer. Clinical implications, diagnostic markers, and therapeutic strategies targeting specific pathways of inflammation are also addressed. This research is intended to serve as a valuable resource for students of medical and biological sciences, healthcare professionals, and researchers interested in immunology and disease mechanisms.


19.06.2025 Volume Issue View more Download
AMIR XUDOYBERDI SHE’RIYATI LEKSIKASINING MAVZUVIY GURUHLARI

Maqolada Qashqadaryolik shoir Amir Xudoyberdi she’riyati leksikasi tahlilga tortilgan. Adib she’riyati leksikasi mavzuviy guruhlarga bo‘lib o‘rganilgan.


19.06.2025 Volume Issue View more Download
KEŃESBAY ABDULAEV DÓRETIWSHILIGINDEGI “ELIM BAR” HÁM “BIZGE KEL” QOSIQLARINIŃ TALIQLAW

Bul maqalada qaraqalpaq kompozitor hám namagerlerdiń bir qansha jazǵan qosıqlarınıń atları haqqında aytıp ótilgen. Bunnan basqa Keńesbay Abdulaev qálemine tiyisli bolǵan «Elim bar» hám «Bizge kel» qosıǵı boyınsha tolıq talıqlaw berilgen.


19.06.2025 Volume Issue View more Download
PARA TAEKVONDOCHILARNING OYOQ ZARBALAR TEZLIGINI RIVOJLANTIRISH

Mazkur ilmiy maqolada para taekvondo sport turi doirasida sportchilarning oyoq zarbalaridagi tezkorlikni oshirishda zamonaviy metod va vositalarning o‘rni atroflicha tahlil qilingan. Tadqiqotda 16–22 yosh oralig‘idagi nogironligi bor sportchilar ishtirokida eksperimental mashg‘ulotlar o‘tkazilib, zarba tezligi, aniqligi va mushak faolligining o‘zgarish dinamikasi kuzatildi. Treninglarda plyometrik yuklamalar, reaksiya tezligini rivojlantirishga xizmat qiluvchi mashqlar, video-analiz, hamda audiovizual stimulyatorlardan foydalanildi. Natijalar sportchilarning zarba berish texnikasi, koordinatsiya va motivatsiya darajasida sezilarli ijobiy o‘zgarishlarni ko‘rsatdi. Tadqiqot asosida para taekvondo sportchilari uchun individuallashtirilgan va moslashtirilgan trening dasturi ishlab chiqildi.


19.06.2025 Volume Issue View more Download
“TANQID, MUNAQQID VA HOZIRGI ADABIY JARAYON” (UMARALI NORMATOV) NOMLI SUHBAT HAQIDA

Ushbu maqolada adabiyotimiz rivojiga o‘zining kata hissasini qo‘shgan adabiyotshunos olim, munaqqid, professor Umarali Normatovning “Tafakkur yog‘dusi” asaridagi suhbatlaridan biri haqida so‘z yuritiladi.


19.06.2025 Volume Issue View more Download
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