Ushbu maqolada O‘zbekistonda sport tadbirlarini tashkil etishdagi ichki imkoniyatlar, davlat siyosati, sport federatsiyalari faoliyati va xalqaro tashkilotlar bilan hamkorlik masalalari tahlil qilinadi. Milliy sport infratuzilmasining takomillashuvi, xalqaro miqyosda e’tirof etilgan musobaqalarni o‘tkazish, xorijiy mutaxassislar bilan tajriba almashinuvi va homiylik hamkorliklari orqali sport rivojiga hissa qo‘shish masalalariga e’tibor qaratilgan.
Mazkur maqolada sport menejmenti sohasida gender tengligi masalalari tahlil qilinadi. Unda ayollarning sport boshqaruvidagi ishtiroki, mavjud to‘siqlar, ilg‘or tajribalar va gender tengligini ta’minlash bo‘yicha takliflar keltirilgan. Maqola sport tizimidagi adolatli va inklyuziv boshqaruvga erishish yo‘llarini ko‘rsatishga qaratilgan.
The automatization of the heart is its fundamental ability to independently generate electrical impulses that initiate heart contractions, without external stimulation from the nervous system. This review is devoted to a comprehensive review of this phenomenon. The main driver of the rhythm is normally the sinoatrial (CA) node, whose cells have unique electrophysiological properties, in particular, the ability to slow spontaneous diastolic depolarization (phase 4 of the action potential). This process is based on the complex dynamics of ion currents, including the "funny" current (If), calcium currents (ICa,T, ICa,L) and potassium currents (IK). The review examines in detail the ionic mechanisms of pacemaker activity, the hierarchy of pacemakers (CA node, atrioventricular node, Gis-Purkinje system) and the phenomenon of suppression of the underlying centers of automatism (overdrive suppression). The mechanisms of regulation of heart rate by the autonomic nervous system (sympathetic and parasympathetic), humoral factors (adrenaline, thyroid hormones) and other influences (temperature, ion balance, hypoxia) are highlighted. The clinical significance of automation is discussed, including pathological conditions such as CA node dysfunction (sinus node weakness syndrome), ectopic foci of automatism, atrial and ventricular arrhythmias associated with abnormal automation, as well as approaches to their diagnosis (ECG) and treatment (antiarrhythmic drugs, artificial pacemakers). In conclusion, modern research directions in this field are considered, including the study of the genetic basis of automatism disorders and the development of biological rhythm drivers.
Mazkur maqolada oʻzbek tiliga soʻnggi yillarda kirib kelgan oʻzlashma soʻzlarning ma'nosi, ularning oʻzbek tilida qay tarzda ishlatilishi hamda milliy imlo qoidalariga moslashtirish jarayoni tahlil qilinadi. Shuningdek, oʻzlashma soʻzlarning lugʻatlarga kiritilishi uchun zarur boʻlgan mezonlar va ular bilan bogʻliq muammolar yoritiladi, yangi oʻzlashmalarni tilimizga moslashtirishda taklif va tavsiyalar ham beriladi.