Ushbu maqolada biofarmatsevtika sohasida yangi avlod dorivor moddalarni yaratishda polimer asosli materiallardan foydalanish asoslari yoritiladi. Polimerlarning farmatsevtik faol moddalar tashuvchisi sifatidagi afzalliklari — ya’ni ularning biokompatibiligi, biodegradatsiyalanuvchanligi, dori moddasining organizmga nazoratli va uzoq muddatli yetkazilishini ta’minlash kabi xususiyatlari chuqur tahlil qilinadi. Maqolada tabiiy va sintetik polimerlar asosida yaratilgan dorivor tizimlarning sintezi, tarkibi, farmakokinetik xususiyatlari hamda ularning davo samaradorligini oshirishdagi roli muhokama qilinadi. Shuningdek, polimer asosli dori shakllarining hozirgi zamon tibbiyotida qo‘llanilishi, ularni ishlab chiqishdagi dolzarb yo‘nalishlar va muammolar tahlil qilinadi. Xususan, nanostrukturalar, mikrokapsulalar, gidrogellar va plyonkalar ko‘rinishidagi polimer bazasidagi dori tashuvchi tizimlar hamda ularning sintezida qo‘llaniladigan kimyoviy va biologik usullar ko‘rib chiqiladi.

Ilimiy maqalada shańaraqta qız balalardı tárbiyalawdıń ózine tán ózgeshelikleri,qızlar tárbiyasında xalıq pedagogikası dereklerinen paydalanıwdıń jolları,usılları oǵada keń sóz etilgen. Haqiyqatındada shıǵıs xalıqları qız balalar tárbiyasına ázel-ázelden úlken itibar berip kelmekte.

This article analyzes the advantages and challenges of applying artificial intelligence (AI) technologies in agriculture. It explores the impact of AI on the agricultural sector, opportunities to improve productivity through the integration of these technologies, and their environmental implications. Moreover, the article provides detailed insights into the difficulties encountered in the effective implementation of AI technologies in agriculture and offers solutions to overcome them. The impact of technological innovations on the lives of rural populations is also highlighted.

The automatization of the heart is its fundamental ability to independently generate electrical impulses that initiate heart contractions, without external stimulation from the nervous system. This review is devoted to a comprehensive review of this phenomenon. The main driver of the rhythm is normally the sinoatrial (CA) node, whose cells have unique electrophysiological properties, in particular, the ability to slow spontaneous diastolic depolarization (phase 4 of the action potential). This process is based on the complex dynamics of ion currents, including the "funny" current (If), calcium currents (ICa,T, ICa,L) and potassium currents (IK). The review examines in detail the ionic mechanisms of pacemaker activity, the hierarchy of pacemakers (CA node, atrioventricular node, Gis-Purkinje system) and the phenomenon of suppression of the underlying centers of automatism (overdrive suppression). The mechanisms of regulation of heart rate by the autonomic nervous system (sympathetic and parasympathetic), humoral factors (adrenaline, thyroid hormones) and other influences (temperature, ion balance, hypoxia) are highlighted. The clinical significance of automation is discussed, including pathological conditions such as CA node dysfunction (sinus node weakness syndrome), ectopic foci of automatism, atrial and ventricular arrhythmias associated with abnormal automation, as well as approaches to their diagnosis (ECG) and treatment (antiarrhythmic drugs, artificial pacemakers). In conclusion, modern research directions in this field are considered, including the study of the genetic basis of automatism disorders and the development of biological rhythm drivers.

Ushbu maqolada O‘zbekistonda sport tadbirlarini tashkil etishdagi ichki imkoniyatlar, davlat siyosati, sport federatsiyalari faoliyati va xalqaro tashkilotlar bilan hamkorlik masalalari tahlil qilinadi. Milliy sport infratuzilmasining takomillashuvi, xalqaro miqyosda e’tirof etilgan musobaqalarni o‘tkazish, xorijiy mutaxassislar bilan tajriba almashinuvi va homiylik hamkorliklari orqali sport rivojiga hissa qo‘shish masalalariga e’tibor qaratilgan.