Human dignity is the intrinsic respect, worth, and significance of the human being essentially or extrinsically determined through the rational capacity, volition, and free will of man. In Afghanistan’s constitutional law, human dignity is essential. Human dignity is the core and fundamental principle of all laws, as defined by the 2004 Constitution, which serves as the mother of law and the source of a nation’s legislation. The main aim of this article is to understand the concept of human dignity in Afghanistan constitutional law, particularly in the context of the 2004 constitution. This study uses a descriptive-analytical method and relies on library-based data collection. The results of this study show that in terms of the wording of the Constitution of the Republic of Poland, human dignity is a human right and one of the most important values forming a basis for the functioning of governance in Afghanistan. The state is obligated to ensure comprehensive protection of human dignity and to prohibit any actions that violate or undermine it, whether in its inherent or acquired form.

This article explores the complex pathophysiological mechanisms underlying the development of kidney failure. It highlights the key roles of hemodynamic changes, cellular injury, inflammation, oxidative stress, and hormonal imbalances in the progression of renal dysfunction. The chronic activation of the renin-angiotensin-aldosterone system and its contribution to fibrosis and nephron loss are discussed in detail. The article also examines how inflammatory processes and oxidative damage exacerbate kidney tissue injury, while hormonal disturbances contribute to systemic complications such as anemia and mineral imbalance. Emphasis is placed on the importance of early detection and targeted treatment strategies to slow disease progression and improve patient outcomes. The review concludes with a discussion on future research directions aimed at developing novel diagnostic markers and therapeutic approaches for kidney failure.

Mazkur maqolada Shayboniylar davlati (1500–1599) davridagi ijtimoiy tuzilma va davlat tomonidan amalga oshirilgan islohotlar tarixiy manbalar asosida tahlil qilinadi. Jamiyatning asosiy qatlamlari – hukmdorlar, diniy ulamolar, harbiylar, dehqonlar va savdogarlar o‘rtasidagi o‘zaro munosabatlar, ularning davlat boshqaruvidagi o‘rni va vazifalari yoritiladi. Shuningdek, ma’muriy, harbiy, yer-soliq va diniy sohalarda olib borilgan islohotlar mazmuni hamda ularning jamiyat barqarorligiga ta’siri ochib beriladi. Maqola ijtimoiy taraqqiyotga ta’sir etgan tarixiy omillarni chuqur anglashga xizmat qiladi.

Emocional sharshaw - bul uzaq dawam etken stress, emocional hám fizikalıq artıqsha júklemeler nátiyjesinde insannıń ruwxiy resurslarınıń tawsılıwı hám sharshaw jaģdayı. Bul maqalada sezimlik sharshawdıń aqıbetleri hám onıń insan organizmine bolǵan qáwip-qáterleri tallanǵan. Maqalada sezimlik sharshawdıń psixologiyalıq, fizikalıq, sociallıq hám kásiplik tarawlardaǵı unamsız tásirleri hám olardı azaytıwdıń nátiyjeli usılları sáwlelendirilgen. Maqala sezimlik sharshawdıń uzaq múddetli aqıbetlerinen saqlanıw hám olardı saplastırıw boyınsha usınıslardı usınadı.

Mazkur maqolada sport tadbirlarida marketing strategiyalarining tutgan o‘rni, ularning qo‘llanilish shakllari va samaradorlik darajasi har tomonlama tahlil qilinadi. Sport sohasi zamonaviy jamiyatda nafaqat sog‘lom turmush tarzini targ‘ib qiluvchi ijtimoiy institut, balki katta iqtisodiy salohiyatga ega bo‘lgan tarmoq sifatida ham maydonga chiqmoqda. Xususan, yirik sport tadbirlarining muvaffaqiyatli tashkil etilishi ularning marketing jihatdan to‘g‘ri rejalashtirilganligiga bog‘liq. Maqolada sport marketingining asosiy strategiyalari — brending, raqamli marketing, homiylik aloqalari, auditoriya bilan ishlash va tomoshabinlar tajribasini boshqarish kabi yo‘nalishlar alohida ko‘rib chiqiladi.