PATHOPHYSIOLOGICAL BASIS AND HORMONAL FACTORS OF THE DEVELOPMENT OF HYPERTENSION

This article explores the pathophysiological mechanisms underlying the development of hypertension, with a special emphasis on the hormonal factors that contribute to elevated blood pressure. Hypertension, one of the most prevalent cardiovascular disorders worldwide, results from a complex interplay between genetic predisposition, environmental influences, and dysregulation of multiple physiological systems. The article discusses how alterations in renal function, vascular resistance, and sympathetic nervous system activity lead to chronic elevation of arterial pressure. Particular attention is given to the renin-angiotensin-aldosterone system (RAAS), vasopressin, and other endocrine factors such as catecholamines and natriuretic peptides. The review also highlights the feedback loops and receptor sensitivities that sustain hypertensive states over time. Understanding these hormonal contributions is essential for identifying therapeutic targets and improving the management of hypertensive patients. Overall, the paper aims to provide a comprehensive view of how hormonal imbalance acts as a key driver in the pathogenesis of hypertension.


20.05.2025 Volume Issue View more Download
CHIDAMLILIK TUSHUNCHASI VA TURLARI

Agar kishi biror bir og‘ir ishni bajarayotgan bo‘lsa, u birmuncha vaqtdan so‘ng bu ishni bajarish tobora qiynlashib borayotganini sezadi. Chetdan qaraganda bu kishining holati ancha o‘zgarganligini ko‘rish mumkin. Bu o‘zgarishni mimika muskullari kuchlanishida, ter paydo bo‘lishida kurish mumkin.ayni vaqtda uning organizmida bimruncha jiddiy fiziologik o‘zgarishlar ham ro‘y beradi. Qiyinchiliklar ko‘payib borishiga karamsdan, kishi iroda kuchi hisobiga dastlabki ish shiddati birmuncha vaqt saqlab turishi mumkin.


20.05.2025 Volume Issue View more Download
SPORT TADBIRLARIDA MARKETING STRATEGIYALARINING AHAMIYATI VA ULARNING SAMARADORLIGI

Mazkur maqolada sport tadbirlarida marketing strategiyalarining tutgan o‘rni, ularning qo‘llanilish shakllari va samaradorlik darajasi har tomonlama tahlil qilinadi. Sport sohasi zamonaviy jamiyatda nafaqat sog‘lom turmush tarzini targ‘ib qiluvchi ijtimoiy institut, balki katta iqtisodiy salohiyatga ega bo‘lgan tarmoq sifatida ham maydonga chiqmoqda. Xususan, yirik sport tadbirlarining muvaffaqiyatli tashkil etilishi ularning marketing jihatdan to‘g‘ri rejalashtirilganligiga bog‘liq. Maqolada sport marketingining asosiy strategiyalari — brending, raqamli marketing, homiylik aloqalari, auditoriya bilan ishlash va tomoshabinlar tajribasini boshqarish kabi yo‘nalishlar alohida ko‘rib chiqiladi.


20.05.2025 Volume Issue View more Download
JISMONIY TARBIYA VA SPORT SOHASIDA RAQAMLI TEXNOLOGIYALARNI QO'LLASHNING YANGI TENDENSIYALARI

Mazkur maqolada jismoniy tarbiya va sport sohasida raqamli texnologiyalarning qo‘llanilishiga oid yangi tendensiyalar, ularning samaradorligi va imkoniyatlari tahlil qilinadi. Axborot-kommunikatsiya texnologiyalarining jadal rivojlanishi sport mashg‘ulotlarini takomillashtirish, sportchilarning salomatligini monitoring qilish, trening jarayonlarini optimallashtirish hamda sport tadbirlarini keng auditoriyaga yetkazishda muhim ahamiyat kasb etmoqda.


20.05.2025 Volume Issue View more Download
ADAPTIVE CONTROL MODELS OF ENERGY SOURCES IN COMMUNICATION SYSTEMS

This article discusses the issues of managing energy sources in modern communication systems through adaptive control models to improve energy efficiency. The possibility of evaluating the energy supply state in real-time, considering the variability of the load and external factors, and developing optimal control strategies is analyzed.


20.05.2025 Volume Issue View more Download
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