Polycystic Ovary Syndrome reproduktiv yoshdagi ayollarda keng tarqalgan endokrin-metabolik kasalliklardan biri hisoblanadi. So‘nggi yillarda Vitamin D tanqisligi ushbu sindrom rivojlanishida muhim patogenetik omil sifatida qaralmoqda. Mazkur maqolada vitamin D ning insulin signalizatsiyasi, steroidogenez, follikulogenez, yallig‘lanish mediatorlari hamda gen ekspressiyasiga ta’siri bilan bog‘liq molekulyar mexanizmlar zamonaviy ilmiy manbalar asosida tahlil qilindi. Adabiyotlar tahliliga ko‘ra, vitamin D yetishmovchiligi insulinrezistentlikni kuchaytiradi, androgenlar sintezini oshiradi hamda ovulyator funksiyaning buzilishiga olib keladi. Bundan tashqari, VDR genlari polimorfizmlarining PTTS rivojlanish xavfi bilan bog‘liqligi aniqlangan. Vitamin D ning immunomodulyator va antioksidant xususiyatlari surunkali yallig‘lanish hamda oksidlovchi stressni kamaytirishda muhim ahamiyat kasb etadi. Olingan ma’lumotlar vitamin D metabolizmi PTTS patogenezining asosiy molekulyar bo‘g‘inlaridan biri ekanligini ko‘rsatadi.

This study is aimed at evaluating the effectiveness of probiotic use after antibiotic therapy in women with bacterial vaginosis (BV). The clinical observation was conducted in women’s health institutions in Andijan region. A total of 62 women participated in the study. In the experimental group, probiotics were administered after antibiotics, whereas the control group received antibiotics only. The results of the 6-month follow-up showed that symptoms disappeared more rapidly in the probiotic group, the vaginal microflora was restored, and the recurrence rate of the disease was significantly reduced. The findings indicate that the use of probiotics in the treatment of BV is effective in the conditions of Uzbekistan and that their introduction into clinical practice is advisable.

Mazkur maqolada kichik maktab yoshidagi bolalarning psixologik xususiyatlari, ularning bilish jarayonlari, hissiy-emotsional holati hamda ijtimoiy munosabatlarining shakllanishi tahlil qilingan. Shuningdek, ushbu yosh davrida diqqat, xotira, tafakkur va motivatsiya jarayonlarining rivojlanishiga ta’sir etuvchi omillar yoritilgan. Ta’lim jarayonida bolaning individual psixologik xususiyatlarini hisobga olishning ahamiyati asoslab berilgan. Maqolada zamonaviy ta’lim muhiti va axborot texnologiyalarining kichik maktab yoshidagi bolalar psixikasiga ta’siri ham ilmiy nuqtai nazardan bayon etilgan.

This article highlights the role and importance of mathematics in preparing academic lyceum students for higher education. It also analyzes the pedagogical potential of mathematics in developing students’ logical thinking, analytical reasoning, problem-solving abilities, and professional competencies. The article discusses the effectiveness of teaching mathematics through modern pedagogical technologies, organizing independent learning, and applying innovative methods during the preparation process for higher education. Furthermore, scientific and methodological recommendations are provided to enhance the theoretical and practical significance of mathematics education in academic lyceums.

В данной статье проанализированы теоретические и практические аспекты системного подхода к организации онкологической помощи населению. Рост эпидемиологической значимости онкологических заболеваний, усложнение методов диагностики и лечения, а также необходимость интеграции многоуровневых медицинских услуг требуют формирования единой системы управления онкологической службой. В исследовании рассмотрены ключевые компоненты организации онкологической помощи: скрининг, ранняя диагностика, мультидисциплинарное ведение пациентов, цифровой мониторинг, реабилитация и паллиативная помощь. На основе международных рекомендаций и опыта развитых стран разработана интеграционная модель онкологической помощи. Результаты исследования подтверждают, что комплексные механизмы управления способствуют повышению качества медицинской помощи, улучшению выживаемости пациентов и эффективности системы здравоохранения.