Abstract. Holmium energy is delivered to the tissue by means of flexible quartz fibers containing a small amount of water and is released in short pulses. The absorbing chromophore for holmium energy is water. The wavelength of 2140 nm and the penetrating ability into the pancreatic tissue to a depth of 0.5 mm provides the necessary effect. At the same time, the further spread of energy is prevented by the presence of cellular and extracellular fluid, which in turn prevents the development of a deep thermal tissue effect [4]. Due to the presence of a large amount of water in the pancreatic tissue and, accordingly, excellent thermal conduction, the surgeon is given the opportunity to apply both ablation and coagulation. The pulse mechanism of energy delivery also contributes to the process of tissue vaporization. Moreover, hemostasis is achieved independently of the coagulation profile of the patient, which is ideal for patients undergoing anticoagulant therapy [4].