Abstract. Wilms tumor (nephroblastoma) is the most prevalent primary malignant renal tumor in children, accounting for approximately 90% of pediatric renal malignancies. Early and accurate diagnosis plays a critical role in the prognosis and overall treatment success. The role of radiological imaging in Wilms tumor extends beyond mere detection; it includes staging, treatment planning, and monitoring response to therapy. This article provides an in-depth analysis of the diagnostic effectiveness of ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) in detecting Wilms tumor in children. Comparative evaluations of each modality’s sensitivity, specificity, and limitations are supported by recent case statistics and clinical findings. An integrated radiological approach can enhance clinical outcomes, reduce unnecessary surgical interventions, and facilitate personalized care strategies.