Abstract. Accordingly, the goal is to determine the relationship of hyperplastic processes with premenopausal age and their manifestations in the form of abnormal uterine bleeding. The study was conducted on 50 premenopausal patients with a history of hyperplastic processes who were treated in the gynecological department of the first multidisciplinary clinic of Samarkand State Medical University during 2021-2022. The study used general clinical, laboratory, instrumental and statistical research methods. The main complaints upon admission to the hospital were heavy vaginal bleeding and pain, and in 30 women (40%) the bleeding was irregular, prolonged, and scanty; almost all patients complained of weakness, fatigue and irritability. In a general blood test, anemia was observed in all of them; in 20% of women, ESR increased to 20 mm/h; in a general urine test, signs of inflammation were observed in 26.5%; in a smear, dysbacteriosis was observed in 36.% of cases. Hormonal imbalance was observed in 45% of women. It was noted that the level of hormones in all examined women was almost 1.5 times lower than in healthy women of the same age. All women were prescribed antihemorrhagic and antianemic treatment. Hyperplasia of the endometrial layer of the uterus in all cases was expressed by abnormal bleeding, the step-by-step treatment of which once again confirms the need for a complete diagnosis. In premenopausal age, we can say that this condition is associated with hormonal imbalance.