Abstract. This scientific article delves into a comprehensive cross-linguistic investigation, offering a detailed analysis of sentence structures in English and Karakalpak languages. Focusing on syntactic, morphological, and semantic dimensions, our study aims to uncover the intricate differences and commonalities that shape the linguistic fabric of these distinct languages. Employing a comparative approach, we explore word order, sentence constituents, and semantic roles, shedding light on how these languages encode and convey meaning within simple sentences. The findings contribute to the broader understanding of linguistic diversity and provide valuable insights for language educators and researchers.