Abstract. Personalized medicine is a field of healthcare that aims to develop diagnostic, treatment, and preventive strategies based on the genetic characteristics, physiological condition, and lifestyle of each individual. This article discusses the concept of personalized medicine, its main directions, advantages, and applications in practice. Areas such as pharmacogenetics, genetic screening, and targeted therapy in oncology are considered essential components of the personalized approach. Additionally, current challenges, ethical considerations, and future prospects of this field are analyzed. The article concludes with reflections on the potential for developing personalized medicine in Uzbekistan.