Abstract. Central Asia is a strategically important region where the interests of major world powers such as Russia, China and the United States intersect. This article analyzes the role of these powers in the integration processes of the region and the impact of their foreign policy on the internal processes in the Central Asian countries. The first part of the article examines the economic, political, and security initiatives supported by Russia, China, and the United States, as well as their strategic interests in the region did. The second part examines the impact of these countries ' foreign policies on political stability, economic development, and social change in Central Asia. The analysis shows that the influence of major Powers is multifaceted and leads to both positive and negative consequences for the countries of the region. Identifying these trends allows for a better understanding of the mechanisms of regional integration and developing more effective interaction strategies to achieve stability and prosperity in Central Asia.